ARG59007
anti-Methylmalonyl-CoA mutase antibody
anti-Methylmalonyl-CoA mutase antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Methylmalonyl-CoA mutase |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Methylmalonyl-CoA mutase |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 492-526 of Human Methylmalonyl-CoA mutase. |
| 偶联标记 | Un-conjugated |
| 別名 | Methylmalonyl-CoA isomerase; MCM; EC 5.4.99.2; Methylmalonyl-CoA mutase, mitochondrial |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | K562 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P16332 Mouse Methylmalonyl-CoA mutase, mitochondrial Swiss-port # P22033 Human Methylmalonyl-CoA mutase, mitochondrial |
|---|---|
| 基因名称 | MUT |
| 全名 | methylmalonyl CoA mutase |
| 背景介绍 | This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species. [UniProt] |
| 细胞定位 | Mitochondrion matrix. [UniProt] |
| 预测分子量 | 83 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG59007 anti-Methylmalonyl-CoA mutase antibody ICC/IF image
Immunofluorescence: 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized HeLa cells stained with ARG59007 anti-Methylmalonyl-CoA mutase antibody (green) at 1:25 dilution. Nuclear counter stain is DAPI (blue).
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ARG59007 anti-Methylmalonyl-CoA mutase antibody WB image
Western blot: 20 µg of K562 cell lysate stained with ARG59007 anti-Methylmalonyl-CoA mutase antibody at 1:2000 dilution.
