ARG67267
anti-Mesothelin antibody [SQab30383]
anti-Mesothelin antibody [SQab30383] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Monoclonal antibody [SQab30383] recognizes Mesothelin. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30383 |
| 同位型 | IgG |
| 靶点名称 | Mesothelin |
| 抗原 | Synthetic peptide. |
| 偶联标记 | Un-conjugated |
| 別名 | MSLN; Mesothelin; MPF; Pre-Pro-Megakaryocyte-Potentiating Factor; CAK1 Antigen; CAK1; Soluble MPF Mesothelin Related Protein; Megakaryocyte Potentiating Factor; SMRP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MSLN |
| 全名 | Mesothelin |
| 背景介绍 | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
| 生物功能 | Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. [Uniprot] |
| 细胞定位 | Cell membrane, Golgi apparatus, Membrane, Secreted. [Uniprot] |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein, Phosphoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG67267 anti-Mesothelin antibody [SQab30383] IHC-P image
Immunohistochemistry: Human Mesothelioma stained with ARG67267 anti-Mesothelin antibody [SQab30383] at 1:100 dilution.
