ARG43712
anti-Mesothelin antibody
anti-Mesothelin antibody for Immunoprecipitation,Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Mesothelin |
|---|---|
| 反应物种 | Ms |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Mesothelin |
| 抗原物种 | Mouse |
| 抗原 | Purified recombinant fragment corresponding to Mouse Mesothelin. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Mesothelin |
| 別名 | MPF; Mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; SMRP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | NIH3T3, Mouse lung | ||||||
| 实际分子量 | 70 kDa, 40 kDa (cleaved) |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Msln |
| 全名 | mesothelin |
| 背景介绍 | This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] |
| 生物功能 | Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. [UniProt] |
| 细胞定位 | Cell membrane, Golgi apparatus, Membrane, Secreted |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | Both MPF and the cleaved form of mesothelin are N-glycosylated. Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG43712 anti-Mesothelin antibody WB image
Western blot: NIH3T3 cell lysate stained with ARG43712 anti-Mesothelin antibody.
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ARG43712 anti-Mesothelin antibody WB image
Western blot: Mouse lung tissue lysate stained with ARG43712 anti-Mesothelin antibody.
