ARG56525
anti-Melanocortin 4 Receptor antibody
anti-Melanocortin 4 Receptor antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Melanocortin 4 Receptor |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Melanocortin 4 Receptor |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide around the N-terminus of Mouse Melanocortin-4 Receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | MC4-R; MC4R; Melanocortin receptor 4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MC4R |
| 全名 | melanocortin 4 receptor |
| 背景介绍 | The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010] |
| 生物功能 | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein [UniProt] |
| 产品亮点 | Related news: Studying obesity and appetite control by quantifying orexigenic and anorexigenic hormones; |
| 预测分子量 | 37 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56525 anti-Melanocortin 4 Receptor antibody WB image
Western blot: 1) 30 µg of Human cerebella cortex pellet, and 2) 30 µg of Human hippocampus homogenate stained with ARG56525 anti-Melanocortin 4 Receptor antibody.
