ARG55379
anti-Melanocortin 3 Receptor antibody
anti-Melanocortin 3 Receptor antibody for Flow cytometry,Western blot and Human
Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Melanocortin 3 Receptor |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Melanocortin 3 Receptor |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 86-112 (Center) of Human Melanocortin 3 Receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | MC3-R; OQTL; OB20; BMIQ9; Melanocortin receptor 3; MC3 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | K562 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MC3R |
| 全名 | melanocortin 3 receptor |
| 背景介绍 | This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 36 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG55379 anti-Melanocortin 3 Receptor antibody WB image
Western blot: 35 µg of K562 cell lysate stained with ARG55379 anti-Melanocortin 3 Receptor antibody.
-
ARG55379 anti-Melanocortin 3 Receptor antibody FACS image
Flow Cytometry: K562 cells stained with ARG55379 anti-Melanocortin 3 Receptor antibody (right histogram) or without primary antibody control (left histogram), followed by incubation with FITC labelled secondary antibody.
