ARG44225
anti-Matrin 3 antibody
anti-Matrin 3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Matrin 3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Matrin 3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human Matrin 3 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Matrin-3 |
| 別名 | MATR3; Matrin 3; KIAA0723; VCPDM; Matrin-3; MGC9105; MPD2; Vocal Cord And Pharyngeal Weakness With Distal Myopathy; Myopathy, Distal 2; ALS21 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MATR3 |
| 全名 | Matrin 3 |
| 背景介绍 | This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. |
| 生物功能 | May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway . |
| 细胞定位 | Nucleus |
| 预测分子量 | 95 kDa |
| 翻译后修饰 | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (9) Click the Picture to Zoom In
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ARG44225 anti-Matrin 3 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG44225 anti-Matrin 3 antibody at 2 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG44225 anti-Matrin 3 antibody at 5 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody WB image
Western blot: MCF-7, SH-SY5Y and RT4 stained with ARG44225 anti-Matrin 3 antibody at 0.25 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody FACS image
Flow Cytometry: HepG2 stained with ARG44225 anti-Matrin 3 antibody at 1 μg/1x10^6 cells dilution.
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ARG44225 anti-Matrin 3 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG44225 anti-Matrin 3 antibody at 2 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody WB image
Western blot: Rat brain stained with ARG44225 anti-Matrin 3 antibody at 0.25 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44225 anti-Matrin 3 antibody at 2 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody WB image
Western blot: Mouse brain stained with ARG44225 anti-Matrin 3 antibody at 0.25 μg/mL dilution.
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ARG44225 anti-Matrin 3 antibody IHC-P image
Immunohistochemistry: Human rectum adenocarcinoma stained with ARG44225 anti-Matrin 3 antibody at 2 μg/mL dilution.
