ARG64429
anti-Mannosidase II antibody
anti-Mannosidase II antibody for Western blot and Human
Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes Mannosidase II |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Mannosidase II |
| 抗原物种 | Human |
| 抗原 | C-KISSDIKSQNR |
| 偶联标记 | Un-conjugated |
| 別名 | Mannosidase alpha class 2A member 1; AMan II; Golgi alpha-mannosidase II; MANA2; Alpha-mannosidase 2; Man II; GOLIM7; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; MANII; EC 3.2.1.114 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MAN2A1 |
| 全名 | mannosidase alpha class 2A member 1 |
| 背景介绍 | This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. [UniProt] |
| 研究领域 | Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 131 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG64429 anti-Mannosidase II antibody WB image
Western blot: 35 µg of Human placenta lysate (in RIPA buffer) stained with ARG64429 anti-Mannosidase II antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.
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ARG64429 anti-Mannosidase II antibody WB image
Western blot: 1). Mock transfection; 2) MAN2A1 (RC220186) expressing plasmid transfected HEK293 cell lysate standed with ARG64429 anti-Mannosidase II antibody.
