ARG59909

anti-MYSM1 antibody

anti-MYSM1 antibody for Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes MYSM1
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MYSM1
抗原物种 Human
抗原 Synthetic peptide within aa. 700 to the C-terminus of Human MYSM1 (NP_001078956.1).
偶联标记 Un-conjugated
別名 Myb-like, SWIRM and MPN domain-containing protein 1; EC 3.4.19.-; Histone H2A deubiquitinase MYSM1; 2ADUB; 2A-DUB

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse brain and Jurkat
实际分子量 105 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 114803 Human MYSM1

GeneID: 320713 Mouse MYSM1

Swiss-port # Q5VVJ2 Human Histone H2A deubiquitinase MYSM1

Swiss-port # Q69Z66 Mouse Histone H2A deubiquitinase MYSM1

基因名称 MYSM1
全名 Myb-like, SWIRM and MPN domains 1
生物功能 Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. [UniProt]
细胞定位 Nucleus. [UniProt]
预测分子量 95 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG59909 anti-MYSM1 antibody WB image

    Western blot: 25 µg of Mouse brain and Jurkat cell lysates stained with ARG59909 anti-MYSM1 antibody at 1:3000 dilution.