ARG56246
anti-MYH9 antibody
anti-MYH9 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MYH9 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MYH9 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MYH9 |
| 偶联标记 | Un-conjugated |
| 別名 | NMHC-II-A; Myosin heavy chain 9; FTNS; Non-muscle myosin heavy chain IIa; Non-muscle myosin heavy chain A; BDPLT6; EPSTS; NMMHCA; MHA; Myosin-9; DFNA17; Myosin heavy chain, non-muscle IIa; NMMHC-IIA; NMMHC II-a; NMMHC-A; Cellular myosin heavy chain, type A |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Jurkat |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MYH9 |
| 全名 | myosin, heavy chain 9, non-muscle |
| 背景介绍 | This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011] |
| 生物功能 | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. [UniProt] |
| 预测分子量 | 227 kDa |
| 翻译后修饰 | ISGylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG56246 anti-MYH9 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human esophagus stained with ARG56246 anti-MYH9 antibody at 1:100 dilution.
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ARG56246 anti-MYH9 antibody WB image
Western blot: Jurkat cell lysate stained with ARG56246 anti-MYH9 antibody.
