ARG40486
anti-MYBPC1 antibody
anti-MYBPC1 antibody for ICC/IF,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MYBPC1 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | ICC/IF, WB |
| 特异性 | At least five isoforms of MYBPC1 are known to exist. This antibody is predicted not to cross-react with other MYBPC family members. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MYBPC1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around 18 aa (N-terminus) of Human MYBPC1. |
| 偶联标记 | Un-conjugated |
| 別名 | LCCS4; MYBPCC; Slow MyBP-C; C-protein, skeletal muscle slow isoform; MYBPCS; Myosin-binding protein C, slow-type |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Rat skeletal muscle |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MYBPC1 |
| 全名 | myosin binding protein C, slow type |
| 背景介绍 | This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. [UniProt] |
| 预测分子量 | 128 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG40486 anti-MYBPC1 antibody ICC/IF image
Immunofluorescence: Mouse skeletal muscle cells stained with ARG40486 anti-MYBPC1 antibody at 20 µg/ml dilution.
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ARG40486 anti-MYBPC1 antibody WB image
Western blot: Rat skeletal muscle tissue lysate stained with ARG40486 anti-MYBPC1 antibody at 1 µg/ml dilution.
