ARG44709
anti-MVK antibody
anti-MVK antibody for Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes MVK. |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | MVK |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | Mevalonate kinase; EC 2.7.1.36; POROK3; MK; MVLK; LRBP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MVK |
| 全名 | mevalonate kinase |
| 背景介绍 | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | May be a regulatory site in cholesterol biosynthetic pathway. [UniProt] |
| 细胞定位 | Cytoplasm. Peroxisome. [UniProt] |
| 翻译后修饰 | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
检测图片 (2) Click the Picture to Zoom In
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ARG44709 anti-MVK antibody WB image
Western blot: Caco2 stained with ARG44709 anti-MVK antibody at 1 µg/mL dilution.
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ARG44709 anti-MVK antibody IP image
Immunoprecipitation: Caco2 lysate immunoprecipitated with 2.5 µg of ARG44709 anti-MVK antibody.
