anti-MUC2 / Mucin 2 antibody [SQab21246]

anti-MUC2 / Mucin 2 antibody [SQab21246] for IHC-Formalin-fixed paraffin-embedded sections and Human


产品描述 Mouse Monoclonal antibody [SQab21246] recognizes MUC2 / Mucin 2
反应物种 Hu
应用 IHC-P
宿主 Mouse
克隆 Monoclonal
克隆号 SQab21246
同位型 IgG
靶点名称 MUC2 / Mucin 2
抗原物种 Human
抗原 A 29-amino acid synthetic peptide containing one repeat unit of 23 amino acids and part of the next repeat of four amino acids in the VNTR (variable number of tandem repeats).
偶联标记 Un-conjugated
別名 MUC-2; MLP; Intestinal mucin-2; SMUC; Mucin-2


应用 推荐稀释比
IHC-P1:100 - 1:200
应用说明 IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂 0.01% Sodium azide
稳定剂 40% Glycerol and 0.05% BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 4583 Human MUC2

Swiss-port # Q02817 Human Mucin-2

基因名称 MUC2
全名 mucin 2, oligomeric mucus/gel-forming
生物功能 Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. [UniProt]
预测分子量 540 kDa
翻译后修饰 O-glycosylated.

May undergo proteolytic cleavage in the outer mucus layer of the colon, contributing to the expanded volume and loose nature of this layer which allows for bacterial colonization in contrast to the inner mucus layer which is dense and devoid of bacteria.

At low pH of 6 and under, undergoes autocatalytic cleavage in vitro in the N-terminal region of the fourth VWD domain. It is likely that this also occurs in vivo and is triggered by the low pH of the late secretory pathway. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG66874 anti-MUC2 / Mucin 2 antibody [SQab21246] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human appendix tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66874 anti-MUC2 / Mucin 2 antibody [SQab21246] for 30 min at RT.