ARG44874
anti-MTHFD2 antibody
anti-MTHFD2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes MTHFD2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | MTHFD2 |
| 抗原物种 | Human |
| 抗原表位 | TIMKPASISE EELLNLINKL NNDDNVDGLL VQLPLPEHID ERRICNAVSP DKDVDGFHVI NVGRMCLDQY SMLPATPWGV WEIIKRTGIP TLGKNVVVAG RSKNVGMPIA MLLHTDGAHE RPGGDATVTI SHRYTPKEQL KKHTILADIV ISAAGIPNLI TADMIKEGAA VIDVGINRVH DPVTAKPKLV GDVDFEGVRQ |
| 偶联标记 | Un-conjugated |
| 別名 | MTHFD2; Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase; Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase, Mitochondrial; NMDMC; NAD-Dependent Methylene Tetrahydrofolate Dehydrogenase Cyclohydrolase |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P13995 Human Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitoc |
|---|---|
| 基因名称 | MTHFD2 |
| 全名 | Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase |
| 背景介绍 | This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009] |
| 生物功能 | Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency. [UniProt] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 翻译后修饰 | Acetylation, Isopeptide bond, Ubl conjugation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG44874 anti-MTHFD2 antibody WB image
Western blot: A-431 stained with ARG44874 anti-MTHFD2 antibody at 1 µg/mL dilution.
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ARG44874 anti-MTHFD2 antibody IHC-P image
Immunohistochemistry: Human kidney stained with ARG44874 anti-MTHFD2 antibody at 5 µg/mL dilution.
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ARG44874 anti-MTHFD2 antibody IP image
Immunoprecipitation: A-431 lysate immunoprecipitated with 2.5 µg of ARG44874 anti-MTHFD2 antibody.
