ARG45915

anti-MTBP antibody

anti-MTBP antibody for Western blot,Flow cytometry and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes MTBP
反应物种 Hu, Ms, Rat
应用 FACS, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MTBP
抗原物种 Human
抗原 Recombinant protein containing to human MTBP.
偶联标记 Un-conjugated
別名 MDM2 Binding Protein; MTBP; Mdm2-binding protein; hMTBP

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 100 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 105837 Mouse MTBP

GeneID: 27085 Human MTBP

Swiss-port # Q8BJS8 Mouse Mdm2-binding protein

Swiss-port # Q96DY7 Human Mdm2-binding protein

基因名称 MTBP
全名 MDM2 Binding Protein
背景介绍 This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012]
生物功能 Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. [UniProt]
预测分子量 102 kDa
翻译后修饰 Phosphoprotein. [UniProt]

检测图片 (4) Click the Picture to Zoom In

  • ARG45915 anti-MTBP antibody WB image

    Western blot: K562 stained with ARG45915 anti-MTBP antibody at 0.5 μg/ml dilution.

  • ARG45915 anti-MTBP antibody FACS image

    Flow Cytometry: PC-3 stained with ARG45915 anti-MTBP antibody at 1 µg/10^6 cells dilution.

  • ARG45915 anti-MTBP antibody WB image

    Western blot: Rat testis stained with ARG45915 anti-MTBP antibody at 0.5 μg/ml dilution.

  • ARG45915 anti-MTBP antibody WB image

    Western blot: Neuro-2a stained with ARG45915 anti-MTBP antibody at 0.5 μg/ml dilution.