ARG66596
anti-MRPS12 antibody
anti-MRPS12 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MRPS12 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MRPS12 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 40-120 of Human MRPS12. |
| 偶联标记 | Un-conjugated |
| 別名 | RPSM12; RPS12; 28S ribosomal protein S12, mitochondrial; MT-RPS12; RPMS12; MRP-S12; S12mt; MPR-S12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 15 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15235 Human 28S ribosomal protein S12, mitochondrial |
|---|---|
| 基因名称 | MRPS12 |
| 全名 | mitochondrial ribosomal protein S12 |
| 背景介绍 | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 预测分子量 | 15 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66596 anti-MRPS12 antibody WB image
Western blot: SH-SY5Y cell lysate stained with ARG66596 anti-MRPS12 antibody at 1:1000 dilution.
