ARG66442
anti-MRGPRX1 / MRGX1 antibody
anti-MRGPRX1 / MRGX1 antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MRGPRX1 / MRGX1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MRGPRX1 / MRGX1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 240-320 of Human MRGX1. |
| 偶联标记 | Un-conjugated |
| 別名 | SNSR4; MRGX1; MGRG2; Sensory neuron-specific G-protein coupled receptor 3/4; GPCR; Mas-related G-protein coupled receptor member X1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 36 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96LB2 Human Mas-related G-protein coupled receptor member X1 |
|---|---|
| 基因名称 | MRGPRX1 |
| 全名 | MAS-related GPR, member X1 |
| 生物功能 | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 36 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG66442 anti-MRGPRX1 / MRGX1 antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG66442 anti-MRGPRX1 / MRGX1 antibody. The picture on the right is blocked with the synthetic peptide.
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ARG66442 anti-MRGPRX1 / MRGX1 antibody WB image
Western blot: MCF7 cell lysate stained with ARG66442 anti-MRGPRX1 / MRGX1 antibody. The lane on the right is blocked with the synthetic peptide.
