ARG44232
anti-MPST antibody
anti-MPST antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MPST |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MPST |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MPST |
| 偶联标记 | Un-conjugated |
| Protein Full name | 3-mercaptopyruvate sulfurtransferase |
| 別名 | MPST; Mercaptopyruvate Sulfurtransferase; TST2; MST 2; TUM1; TRNA Thiouridin Modification Protein 1; 3-Mercaptopyruvate Sulfurtransferase; Human Liver Rhodanese; Testicular Tissue Protein Li 200; EC 2.8.1.2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P25325 Human 3-mercaptopyruvate sulfurtransferase |
|---|---|
| 基因名称 | MPST |
| 全名 | Mercaptopyruvate Sulfurtransferase |
| 背景介绍 | This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. |
| 生物功能 | Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynthesis. Acts as an antioxidant. In combination with cysteine aminotransferase (CAT), contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain, retina and vascular endothelial cells. Hydrogen sulfide H2S is an important synaptic modulator, signaling molecule, smooth muscle contractor and neuroprotectant. Its production by the 3MST/CAT pathway is regulated by calcium ions. |
| 细胞定位 | Cytoplasm, Mitochondrion, Synapse, Synaptosome |
| 预测分子量 | 33 kDa |
| 翻译后修饰 | Acetylation, Disulfide bond, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44232 anti-MPST antibody ICC/IF image
Immunofluorescence: PC3 stained with ARG44232 anti-MPST antibody at 5 μg/ml dilution.
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ARG44232 anti-MPST antibody WB image
Western blot: HepG2 stained with ARG44232 anti-MPST antibody at 0.5 μg/mL dilution.
