ARG42605
anti-MOSC1 antibody
anti-MOSC1 antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MOSC1 |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MOSC1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human MOSC1. |
| 偶联标记 | Un-conjugated |
| 別名 | Mitochondrial amidoxime-reducing component 1; EC 1.-.-.-; MOSC domain-containing protein 1; MOSC1; Molybdenum cofactor sulfurase C-terminal domain-containing protein 1; Moco sulfurase C-terminal domain-containing protein 1; mARC1 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | NIH/3T3 | ||||
| 实际分子量 | ~ 37 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6NZQ8 Mouse E3 ubiquitin-protein ligase MARCH1 Swiss-port # Q9CW42 Mouse Mitochondrial amidoxime-reducing component 1 |
|---|---|
| 基因名称 | MARC1 |
| 全名 | mitochondrial amidoxime reducing component 1 |
| 生物功能 | Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:19053771, PubMed:21029045, PubMed:30397129). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed:19053771). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed:21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed:21029045, PubMed:19053771). [UniProt] |
| 细胞定位 | Mitochondrion outer membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Mitochondrial import is mediated by AA 1-40 and requires ATP. [UniProt] |
| 预测分子量 | 37 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG42605 anti-MOSC1 antibody WB image
Western blot: NIH/3T3 cell lysate stained with ARG42605 anti-MOSC1 antibody at 1:1000 diluiton, overnight at 4°C.
