ARG41051
anti-MOGS / GCS1 antibody
anti-MOGS / GCS1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MOGS / GCS1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MOGS / GCS1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 60-320 of Human MOGS (NP_006293.2). |
| 偶联标记 | Un-conjugated |
| 別名 | GCS1; DER7; Processing A-glucosidase I; CDG2B; CWH41; Mannosyl-oligosaccharide glucosidase; EC 3.2.1.106 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | BxPC-3 | ||||
| 实际分子量 | 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13724 Human Mannosyl-oligosaccharide glucosidase Swiss-port # Q80UM7 Mouse Mannosyl-oligosaccharide glucosidase |
|---|---|
| 基因名称 | MOGS |
| 全名 | mannosyl-oligosaccharide glucosidase |
| 背景介绍 | This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| 生物功能 | Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Single-pass type II membrane protein. [UniProt] |
| 预测分子量 | 92 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41051 anti-MOGS / GCS1 antibody WB image
Western blot: 25 µg of BxPC-3 cell lysate stained with ARG41051 anti-MOGS / GCS1 antibody at 1:3000 dilution.
