ARG44180
anti-MNAT1 antibody
anti-MNAT1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MNAT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MNAT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MNAT1 |
| 偶联标记 | Un-conjugated |
| Protein Full name | CDK-activating kinase assembly factor MAT1 |
| 別名 | MNAT1; MNAT1 Component Of CDK Activating Kinase; RNF66; MAT1; MNAT CDK-Activating Kinase Assembly Factor 1; MNAT1, CDK Activating Kinase Assembly Factor; CDK-Activating Kinase Assembly Factor MAT1; Menage A Trois 1 (CAK Assembly Factor); CDK7/Cyclin-H Assembly Factor; RING Finger Protein MAT1; RING Finger Protein 66; CAP35; Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis); Menage A Trois-Like Protein 1 Cyclin H Assembly Factor; Menage A Trois Homolog 1, Cyclin H Assembly Factor; CDK-Activating Kinase Assembly Factor; Cyclin G1 Interacting Protein; Cyclin-G1-Interacting Protein; Menage A Trois; TFB3; P35; P36 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P51948 Human CDK-activating kinase assembly factor MAT1 Swiss-port # P51949 Mouse CDK-activating kinase assembly factor MAT1 |
|---|---|
| 基因名称 | MNAT1 |
| 全名 | Mnat1 Component Of Cdk Activating Kinase |
| 背景介绍 | The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. |
| 细胞定位 | Nucleus |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (5) Click the Picture to Zoom In
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ARG44180 anti-MNAT1 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44180 anti-MNAT1 antibody at 5 μg/mL dilution.
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ARG44180 anti-MNAT1 antibody WB image
Western blot: A431, HeLa and A375 stained with ARG44180 anti-MNAT1 antibody at 0.25 μg/mL dilution.
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ARG44180 anti-MNAT1 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44180 anti-MNAT1 antibody at 1 μg/1x10^6 cells dilution.
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ARG44180 anti-MNAT1 antibody WB image
Western blot: Rat testis and RH35 stained with ARG44180 anti-MNAT1 antibody at 0.25 μg/mL dilution.
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ARG44180 anti-MNAT1 antibody WB image
Western blot: Mouse testis and NIH/3T3 stained with ARG44180 anti-MNAT1 antibody at 0.25 μg/mL dilution.
