ARG45371
anti-MMRN2 antibody [2063E2A11]
anti-MMRN2 antibody [2063E2A11] for ICC/IF,IHC-Frozen sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [2063E2A11] recognizes MMRN2 |
|---|---|
| 反应物种 | Ms |
| 应用 | ICC/IF, IHC-Fr |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 2063E2A11 |
| 靶点名称 | MMRN2 |
| 抗原物种 | Mouse |
| 抗原 | Recombinant Mouse MMRN2. |
| 偶联标记 | Un-conjugated |
| 別名 | MMRN2; Multimerin 2; Elastin Microfibril Interfacer 3; EndoGlyx-1; EMILIN3; Elastin Microfibril Interface Located Protein 3; EndoGlyx-1 P125/P140 Subunit; Multimerin-2; FLJ13465; EMILIN-3; EMILIN-Like Protein EndoGlyx-1; EndoGlyx-1 P125/P140 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.1 - 1.0 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MMRN2 |
| 全名 | Multimerin 2 |
| 背景介绍 | This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012] |
| 生物功能 | Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor. |
| 细胞定位 | Extracellular matrix; Secreted. [UniProt] |
| 预测分子量 | 105 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45371 anti-MMRN2 antibody [2063E2A11] IHC-Fr image
Immunohistochemistry: Frozen Mouse lymph node stained with ARG45371 anti-MMRN2 antibody [2063E2A11].
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ARG45371 anti-MMRN2 antibody [2063E2A11] ICC/IF image
Immunofluorescence: Mouse brain endothelial stained with ARG45371 anti-MMRN2 antibody [2063E2A11].
