anti-MMP9 antibody [SB15c]
anti-MMP9 antibody [SB15c] for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Brain Injury IHC Study antibody
|产品描述||Mouse Monoclonal antibody [SB15c] recognizes MMP9|
|应用||ELISA, ICC/IF, IHC-P, WB|
|抗原||Recombinant full length Human MMP-9|
|別名||Matrix metalloproteinase-9; 92 kDa gelatinase; MMP-9; Gelatinase B; GELB; CLG4B; MANDP2; EC 220.127.116.11; 92 kDa type IV collagenase|
|应用说明||* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.|
|缓冲液||BBS (pH 8.2)|
|存放说明||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|注意事项||For laboratory research only, not for drug, diagnostic or other use.|
|全名||matrix metallopeptidase 9|
|背景介绍||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]|
|生物功能||May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. [UniProt]|
|产品亮点||Related Antibody Duos and Panels:
ARG30315 Brain Injury IHC Marker Antibody Duo (GFAP, MMP9)
MMP9 antibodies; MMP9 ELISA Kits; MMP9 Duos / Panels; Anti-Mouse IgG secondary antibodies;
|研究领域||Brain Injury IHC Study antibody|
|翻译后修饰||Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
N- and O-glycosylated.
检测图片 (2) Click the Picture to Zoom In
ARG22191 anti-MMP9 antibody [SB15c] IHC-P image
Immunohistochemistry: Paraffin-embedded Human gastric cancer tissue stained with ARG21961 Mouse IgG2a Isotype Control antibody [HOPC-1] (left) and ARG22191 anti-MMP9 antibody [SB15c] (right) followed by ARG23705 Goat anti-Mouse IgG2a (HRP) (pre-adsorbed), DAB and hematoxylin.