ARG44872
anti-MLH3 antibody
anti-MLH3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes MLH3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | MLH3 |
| 抗原物种 | Human |
| 抗原表位 | YEKQQAQGSG |
| 偶联标记 | Un-conjugated |
| 別名 | MLH3; MutL Homolog 3; DNA Mismatch Repair Protein Mlh3; MutL (E. Coli) Homolog 3; MutL Homolog 3 (E. Coli); MutL Protein Homolog 3; HNPCC7 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MLH3 |
| 全名 | MutL Homolog 3 |
| 背景介绍 | This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Probably involved in the repair of mismatches in DNA. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG44872 anti-MLH3 antibody IHC-P image
Immunohistochemistry: Human endometrium stained with ARG44872 anti-MLH3 antibody at 10 µg/mL dilution.
