ARG44988
anti-MIZ1 antibody
anti-MIZ1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes MIZ1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | MIZ1 |
| 抗原物种 | Human |
| 抗原表位 | GSEVSVVTVD DMVTLATEAL AATAVTQLTV VPVGAAVTAD ETEVLKAEIS KAVKQVQEED PNTHILYACD SCGDKFLDAN SLAQHVRIHT AQALVMFQTD |
| 偶联标记 | Un-conjugated |
| 別名 | ZBTB17; Zinc Finger And BTB Domain Containing17; Zinc Finger Protein60; PHZ-67; ZNF151; ZNF60; MIZ1; Zinc Finger And BTB Domain-Containing Protein17; Zinc Finger Protein151 (PHZ-67); Myc-Interacting Zinc Finger Protein1; Myc-Interacting Zn Finger Protein-1; Zinc Finger Protein151; MIZ-1; Miz-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13105 Human Zinc finger and BTB domain-containing protein 17 |
|---|---|
| 基因名称 | ZBTB17 |
| 全名 | Zinc Finger And BTB Domain Containing17 |
| 背景介绍 | This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome18. [provided by RefSeq, Jul2008] |
| 生物功能 | Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 isoform3/ZNF509S1. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44988 anti-MIZ1 antibody IHC-P image
Immunohistochemistry: Human lung stained with ARG44988 anti-MIZ1 antibody at 5 µg/mL dilution.
