ARG56687

anti-MIP4 antibody

anti-MIP4 antibody for ELISA,Neutralizing,Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes MIP4
反应物种 Hu
应用 ELISA, Neut, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MIP4
抗原物种 Human
抗原 E.coli derived Recombinant Human MIP-4 (CCL18).
(QVGTNKELCC LVYTSWQIPQ KFLVDYSETS PQCPKPGVIL LTKRGRQICA DPNKKWVQKY ISDLKLNA)
偶联标记 Un-conjugated
別名 Small-inducible cytokine A18; 3-69; PARC; Alternative macrophage activation-associated CC chemokine 1; Macrophage inflammatory protein 4; SCYA18; Dendritic cell chemokine 1; CC chemokine PARC; 4-69; 1-68; C-C motif chemokine 18; DC-CK1; AMAC1; Pulmonary and activation-regulated chemokine; AMAC-1; DCCK1; MIP-4; CKb7

应用说明

应用建议
应用 推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG56796 as a detection antibody
Neut8.0 - 10.0 µg/ml (To yield [ND50] of the biological activity of hMIP - 4 (100.0 ng/ml) )
WB0.1 - 0.2 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.2)
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 6362 Human CCL18

Swiss-port # P55774 Human C-C motif chemokine 18

基因名称 CCL18
全名 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
背景介绍 This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
生物功能 Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. [UniProt]
预测分子量 10 kDa
翻译后修饰 The Cys-30/Cys-54 disulfide bond is required for activity.

检测图片 (2) Click the Picture to Zoom In

  • ARG56687 anti-MIP4 antibody WB image

    Western blot: 250 - 0.24 ng of Human MIP-4 stained with ARG56687 anti-MIP4 antibody, under reducing conditions.

  • ARG56687 anti-MIP4 antibody WB image

    Western blot: 250 - 0.24 ng of Human MIP-4 stained with ARG56687 anti-MIP4 antibody, under non-reducing conditions.