ARG44146
anti-MICALL2 antibody
anti-MICALL2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal recognizes MICALL2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MICALL2 |
| 抗原物种 | Human |
| 抗原 | Human MICALL2 recombinant protein (Position: K132-Q741). |
| 偶联标记 | Un-conjugated |
| 別名 | MICALL2; MICAL Like; MICAL-L2; JRAB; Junctional Rab13-Binding Protein; Molecule Interacting With CasL-Like 2; MICAL-Like Protein 2; MGC46023; FLJ23471 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MICALL2 |
| 全名 | MICAL Like 2 |
| 背景介绍 | Enables filamin binding activity. Involved in positive regulation of protein targeting to mitochondrion. Predicted to be located in several cellular components, including bicellular tight junction; neuron projection; and recycling endosome. Predicted to colocalize with stress fiber. |
| 生物功能 | Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth. |
| 细胞定位 | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Endosome, Membrane, Tight junction |
| 预测分子量 | 98 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG44146 anti-MICALL2 antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44146 anti-MICALL2 antibody at 2 μg/ml dilution.
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ARG44146 anti-MICALL2 antibody WB image
Western blot: U20S and K562 stained with ARG44146 anti-MICALL2 antibody at 0.5 μg/ml dilution.
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ARG44146 anti-MICALL2 antibody FACS image
Flow Cytometry: K562 stained with ARG44146 anti-MICALL2 antibody at 1 µg/10^6 cells dilution.
