ARG21056
anti-MHC Class II antibody [NIMR-4]
anti-MHC Class II antibody [NIMR-4] for Flow cytometry,ICC/IF,IHC-Frozen sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [NIMR-4] recognizes MHC Class II |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, ICC/IF, IHC-Fr |
| 特异性 | Mouse MHC Class II. The clone NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | NIMR-4 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | MHC Class II |
| 抗原物种 | Mouse |
| 偶联标记 | Un-conjugated |
| 別名 | AI323765; H-2Ea; MHC-H2-Ea; H2-Ea; I-Ealpha; H-2 class II histocompatibility antigen, E-U alpha chain; Ia3; E-alpha-f; Ia-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | BBS (pH 8.2) |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
GeneID: 100504404 Mouse H2-Ea-ps Swiss-port # P14439 Mouse H-2 class II histocompatibility antigen, E-U alpha chain |
|---|---|
| 基因名称 | H2-Ea-ps |
| 全名 | histocompatibility 2, class II antigen E alpha, pseudogene |
| 背景介绍 | This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5' end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2011] |
| 预测分子量 | 29 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG21056 anti-MHC Class II antibody [NIMR-4] FACS image
Flow Cytometry: BALB/c Mouse splenocytes stained with ARG21056 anti-MHC Class II antibody [NIMR-4] followed by Mouse anti-Rat IgG2b antibody (Alexa Fluor® 488).
