ARG21070

anti-MHC Class II I Ad antibody [34-5-3]

anti-MHC Class II I Ad antibody [34-5-3] for Blocking,Cellular activation ,Flow cytometry,Immunoprecipitation and Mouse

概述

产品描述 Mouse Monoclonal antibody [34-5-3] recognizes MHC Class II I Ad
反应物种 Ms
应用 BL, Cell-Act , FACS, IP
特异性 Mouse I-Ad. The clone 34-5-3 reacts with the β chain of the I-Ad MHC class II alloantigen. It cross-reacts with I-Ab and with cells from mice of the H-2p and H-2q halotypes.
宿主 Mouse
克隆 Monoclonal
克隆号 34-5-3
同位型 IgG2a, kappa
靶点名称 MHC Class II I Ad
抗原物种 Mouse
抗原 (C57BL/6 x DBA/2)F1 mouse splenocytes
偶联标记 Un-conjugated
別名 AI323765; H-2Ea; MHC-H2-Ea; H2-Ea; I-Ealpha; H-2 class II histocompatibility antigen, E-U alpha chain; Ia3; E-alpha-f; Ia-3

应用说明

应用建议
应用 推荐稀释比
BLAssay-dependent
Cell-Act Assay-dependent
FACS< 1 µg/10^6 cells
IPAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 BBS (pH 8.2)
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 100504404 Mouse H2-Ea-ps

Swiss-port # P14439 Mouse H-2 class II histocompatibility antigen, E-U alpha chain

基因名称 H2-Ea-ps
全名 histocompatibility 2, class II antigen E alpha, pseudogene
背景介绍 This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5' end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2011]
预测分子量 29 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG21070 anti-MHC Class II I Ad antibody [34-5-3] FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG21070 anti-MHC Class II I Ad antibody [34-5-3] and ARG20819 anti-CD3e antibody [C363.29B] (PE).