ARG21063
anti-MHC Class II I Ab antibody [25-9-3] (PE)
anti-MHC Class II I Ab antibody [25-9-3] (PE) for Flow cytometry,IHC-Frozen sections and Mouse
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [25-9-3] recognizes MHC Class II I Ab |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, IHC-Fr |
| 特异性 | Mouse I-Ab. The clone 25-9-3 reacts specifically with the I-Ab haplotype of MHC Class II molecules. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 25-9-3 |
| 同位型 | IgM, kappa |
| 靶点名称 | MHC Class II I Ab |
| 抗原物种 | Mouse |
| 抗原 | C3H.SW mouse splenocytes |
| 偶联标记 | PE |
| 別名 | AI323765; H-2Ea; MHC-H2-Ea; H2-Ea; I-Ealpha; H-2 class II histocompatibility antigen, E-U alpha chain; Ia3; E-alpha-f; Ia-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
GeneID: 100504404 Mouse H2-Ea-ps Swiss-port # P14439 Mouse H-2 class II histocompatibility antigen, E-U alpha chain |
|---|---|
| 基因名称 | H2-Ea-ps |
| 全名 | histocompatibility 2, class II antigen E alpha, pseudogene |
| 背景介绍 | This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5' end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2011] |
| 预测分子量 | 29 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG21063 anti-MHC Class II I Ab antibody [25-9-3] (PE) FACS image
Flow Cytometry: C57BL/6 Mouse splenocytes stained with ARG21063 anti-MHC Class II I Ab antibody [25-9-3] (PE) and ARG20817 anti-CD3e antibody [C363.29B] (FITC).
