ARG59037
anti-MGST1 antibody
anti-MGST1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MGST1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MGST1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 42-75 of Human MGST1 (KVFANPEDCVAFGKGENAKKYLRTDDRVERVRRA). |
| 偶联标记 | Un-conjugated |
| 別名 | Microsomal GST-1; EC 2.5.1.18; Microsomal glutathione S-transferase 1; MGST; MGST-I; Microsomal GST-I; GST12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MGST1 |
| 全名 | microsomal glutathione S-transferase 1 |
| 背景介绍 | The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012] |
| 生物功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity. [UniProt] |
| 细胞定位 | Microsome. Mitochondrion outer membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 18 kDa |
| 翻译后修饰 | Peroxynitrite induces nitration at Tyr-93 which activates the enzyme. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59037 anti-MGST1 antibody WB image
Western blot: 50 µg of Rat liver, 50 µg of Mouse liver and 40 µg of HepG2 lysates stained with ARG59037 anti-MGST1 antibody at 0.5 µg/ml dilution.
