ARG44143
anti-MGAT4B antibody
anti-MGAT4B antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
产品描述 | Rabbit Polyclonal recognizes MGAT4B |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | MGAT4B |
抗原物种 | Human |
抗原 | Human MGAT4B recombinant protein (Position: Q31-D548). |
偶联标记 | Un-conjugated |
別名 | MGAT4B; Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B; UDP-N-Acetylglucosamine: Alpha-1,3-D-Mannoside Beta-1,4-N-Acetylglucosaminyltransferase IVb; Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isoenzyme B; Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isozyme B; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IVb; N-Acetylglucosaminyltransferase IVb; GlcNAc-T IVb; EC 2.4.1.145; GnT-Ivb; UDP-N-Acetylglucosamine: Alpha-1,3-D-Mannoside Beta-1,4-N-Acetylglucosaminyltransferase IV; Alpha-1,3-Mannosyl-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase; Aminyltransferase; GNT-IVB; GnT-IVb; GNT-IV |
应用说明
应用建议 |
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应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # Q812F8 Mouse Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Swiss-port # Q9UQ53 Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B |
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基因名称 | MGAT4B |
全名 | Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B |
背景介绍 | This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. |
生物功能 | Glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. |
细胞定位 | Golgi apparatus, Membrane |
预测分子量 | 63 kDa |
翻译后修饰 | Glycoprotein |
检测图片 (4) Click the Picture to Zoom In
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ARG44143 anti-MGAT4B antibody IHC-P image
Immunohistochemistry: Human glioma stained with ARG44143 anti-MGAT4B antibody at 2 μg/ml dilution.
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ARG44143 anti-MGAT4B antibody WB image
Western blot: HepG2, RT4 and A431 stained with ARG44143 anti-MGAT4B antibody at 0.5 μg/ml dilution.
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ARG44143 anti-MGAT4B antibody WB image
Western blot: Rat kidney stained with ARG44143 anti-MGAT4B antibody at 0.5 μg/ml dilution.
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ARG44143 anti-MGAT4B antibody WB image
Western blot: Mouse kidney stained with ARG44143 anti-MGAT4B antibody at 0.5 μg/ml dilution.