ARG59338
anti-MGA antibody
anti-MGA antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MGA |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Bov, Dog, Hrs, Mk, Rb |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MGA |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 2376-2415 of Human MGA. (QKEAEAFAYYRRTHTANERRRRGEMRDLFEKLKITLGLLH) |
| 偶联标记 | Un-conjugated |
| 別名 | MXD5; MAD5; MAX dimerization protein 5; MAX gene-associated protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MGA |
| 全名 | MGA, MAX dimerization protein |
| 生物功能 | Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 336 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59338 anti-MGA antibody WB image
Western blot: HeLa, MCF-7 and SW620 whole cell lysates stained with ARG59338 anti-MGA antibody at 0.5 µg/ml dilution.
