ARG43773
anti-METRNL antibody
anti-METRNL antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes METRNL |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | METRNL |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to aa. Q46-D311 of Human METRNL. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Meteorin-like protein |
| 別名 | METRNL; Subfatin; meteorin like, glial cell differentiation regulator; Cometin; Meteorin-Like Protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 34 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.03% Proclin 300 and 50% Glycerol. |
| 抗菌剂 | 0.03% Proclin 300 |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | METRNL |
| 全名 | meteorin like, glial cell differentiation regulator |
| 背景介绍 | Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; energy homeostasis; and positive regulation of brown fat cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures (By similarity). [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 34.4 kDa |
| 翻译后修饰 | Disulfide bond |
检测图片 (3) Click the Picture to Zoom In
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ARG43773 anti-METRNL antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue stained with ARG43773 anti-METRNL antibody at 1:100 dilution.
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ARG43773 anti-METRNL antibody WB image
Western blot: Mouse brain tissue lysates stained with ARG43773 anti-METRNL antibody at 1:500 dilution.
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ARG43773 anti-METRNL antibody WB image
Western blot: Rat Germ gland tissue lysate stained with ARG43773 anti-METRNL antibody at 1:500 dilution.
