ARG63353
anti-MEL18 / PCGF2 antibody
anti-MEL18 / PCGF2 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes MEL18 / PCGF2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow, Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MEL18 / PCGF2 |
| 抗原物种 | Human |
| 抗原 | C-KMTVNGAPVPPLT |
| 偶联标记 | Un-conjugated |
| 別名 | RING finger protein 110; Polycomb group RING finger protein 2; ZNF144; MEL-18; RNF110; Zinc finger protein 144; DNA-binding protein Mel-18 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P35227 Human Polycomb group RING finger protein 2 |
|---|---|
| 背景介绍 | The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | Phosphorylated. Homodimer formation is regulated by phosphorylation state with unphosphorylated protein forming homodimers (By similarity). |
检测图片 (2) Click the Picture to Zoom In
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ARG63353 anti-MEL18 / PCGF2 antibody WB image
Western Blot: Human Lung lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63353 anti-MEL18 antibody at 1 µg/ml dilution.
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ARG63353 anti-MEL18 / PCGF2 antibody WB image
Western blot: 30 µg of A549 (A) and PD19 (B) cell lysates (in RIPA buffer) stained with ARG63353 anti-MEL18 / PCGF2 antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
