ARG43092

anti-MCUR1 antibody

anti-MCUR1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes MCUR1
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MCUR1
抗原物种 Human
抗原 Synthetic peptide corresponding to a sequence of Human MCUR1. (ATQQAEIIVSALVKILEANMDIVYKDMVTKMQQE)
偶联标记 Un-conjugated
別名 CCDC90A; C6orf79; Mitochondrial calcium uniporter regulator 1; Coiled-coil domain-containing protein 90A, mitochondrial

应用说明

应用建议
应用 推荐稀释比
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
应用说明 IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 ~ 40 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 63933 Human MCUR1

GeneID: 76137 Mouse MCUR1

Swiss-port # Q96AQ8 Human Mitochondrial calcium uniporter regulator 1

Swiss-port # Q9CXD6 Mouse Mitochondrial calcium uniporter regulator 1

基因名称 MCUR1
全名 mitochondrial calcium uniporter regulator 1
生物功能 Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion (PubMed:23178883, PubMed:26445506, PubMed:27184846, PubMed:26976564). Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU (PubMed:23178883). Probably involved in the assembly of the membrane components of the uniporter complex (uniplex) (PubMed:27184846). [UniProt]
细胞定位 Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt]
预测分子量 40 kDa

检测图片 (6) Click the Picture to Zoom In

  • ARG43092 anti-MCUR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human oesophagus squama cancer tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43092 anti-MCUR1 antibody at 1 µg/ml dilution, overnight at 4°C.

  • ARG43092 anti-MCUR1 antibody WB image

    Western blot: 50 µg of sample under reducing conditions. HeLa, MDA-MB-231, HL-60, MDA-MB-453, A431, Caco-2, Rat spleen, Mouse lung and Ana-1 whole cell lysates stained with ARG43092 anti-MCUR1 antibody at 0.5 µg/ml dilution, overnight at 4°C.

  • ARG43092 anti-MCUR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovary cancer tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43092 anti-MCUR1 antibody at 1 µg/ml dilution, overnight at 4°C.

  • ARG43092 anti-MCUR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human placenta tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43092 anti-MCUR1 antibody at 1 µg/ml dilution, overnight at 4°C.

  • ARG43092 anti-MCUR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human tonsil tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43092 anti-MCUR1 antibody at 1 µg/ml dilution, overnight at 4°C.

  • ARG43092 anti-MCUR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung cancer tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43092 anti-MCUR1 antibody at 1 µg/ml dilution, overnight at 4°C.