ARG45907
anti-MCPH1 antibody
anti-MCPH1 antibody for Western blot,ICC/IF,Flow cytometry and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MCPH1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MCPH1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human MCPH1. |
| 偶联标记 | Un-conjugated |
| 別名 | Microcephalin 1; MCPH1; Microcephalin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 93 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MCPH1 |
| 全名 | Microcephalin 1 |
| 背景介绍 | This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] |
| 生物功能 | Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex. [UniProt] |
| 细胞定位 | Cytoplasm; Cytoskeleton. [UniProt] |
| 预测分子量 | 93 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45907 anti-MCPH1 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45907 anti-MCPH1 antibody at 5 μg/ml dilution.
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ARG45907 anti-MCPH1 antibody WB image
Western blot: Hela stained with ARG45907 anti-MCPH1 antibody at 0.5 μg/ml dilution.
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ARG45907 anti-MCPH1 antibody FACS image
Flow Cytometry: 293T stained with ARG45907 anti-MCPH1 antibody at 1 µg/10^6 cells dilution.
