ARG41330
anti-MCOLN1 / TRPML1 antibody
anti-MCOLN1 / TRPML1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MCOLN1 / TRPML1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Gpig, Hrs, Pig, Rb |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MCOLN1 / TRPML1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminal region of Human MCOLN1 / TRPML1. (within the following region: FRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYV) |
| 偶联标记 | Un-conjugated |
| 別名 | ML4; MLIV; Mucolipidin; TRPM-L1; MG-2; TRP-ML1; Mucolipin-1; MST080; MSTP080; TRPML1 |
应用说明
| 预测反应性说明 | Predicted Homology Based On Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea pig: 93%; Horse: 93%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93% | ||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Human fetal lung | ||||
| 实际分子量 | ~ 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MCOLN1 |
| 全名 | mucolipin 1 |
| 背景介绍 | This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. [provided by RefSeq, Oct 2009] |
| 生物功能 | Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis. [UniProt] |
| 细胞定位 | Late endosome membrane; Lysosome membrane; Cytoplasmic vesicle membrane; Cell projection, phagocytic cup. Cytoplasmic vesicle, phagosome membrane; Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 65 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41330 anti-MCOLN1 / TRPML1 antibody WB image
Western blot: Human fetal lung lysate stained with ARG41330 anti-MCOLN1 / TRPML1 antibody at 1 µg/ml dilution.
