ARG43908
anti-MCL1 antibody
anti-MCL1 antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MCL1 |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MCL1 |
| 抗原物种 | Human |
| 抗原 | Human MCL1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Induced myeloid leukemia cell differentiation protein Mcl-1 |
| 別名 | MCL1; MCL1 Apoptosis Regulator, BCL2 Family Member; BCL2L3; Mcl-1; Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1; Myeloid Cell Leukemia Sequence 1 (BCL2-Related); MCL1, BCL2 Family Apoptosis Regulator; Bcl-2-Related Protein EAT/Mcl1; Myeloid Cell Leukemia 1; Bcl-2-Like Protein 3; Bcl2-L-3; Mcl1/EAT; BCL2 Family Apoptosis Regulator; Myeloid Cell Leukemia ES; MCL1-ES; MCL1L; MCL1S; EAT; TM |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q07820 Human Induced myeloid leukemia cell differentiation protein Mcl-1 Swiss-port # Q9Z1P3 Rat Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
|---|---|
| 基因名称 | MCL1 |
| 全名 | MCL1 Apoptosis Regulator, BCL2 Family Member |
| 背景介绍 | This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010] |
| 生物功能 | Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. |
| 细胞定位 | Cytoplasm, Membrane, Mitochondrion, Nucleus |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (4) Click the Picture to Zoom In
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ARG43908 anti-MCL1 antibody ICC/IF image
Immunofluorescence: PC-3 cells stained with ARG43908 anti-MCL1 antibody at 5 μg/ml dilution.
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ARG43908 anti-MCL1 antibody WB
Western blot: Raji, Ramos and MCF-7 stained with ARG43908 anti-MCL1 antibody at 0.5 μg/mL dilution.
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ARG43908 anti-MCL1 antibody FACS image
Flow Cytometry: RT4 cells stained with ARG43908 anti-MCL1 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43908 anti-MCL1 antibody WB
Western blot: Rat stomach and Rat kidney with ARG43908 anti-MCL1 antibody at 0.5 μg/mL dilution.
