ARG44227

anti-MCCC2 antibody

anti-MCCC2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes MCCC2
反应物种 Hu, Ms, Rat
应用 FACS, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MCCC2
抗原物种 Human
抗原 Recombinant protein of Human MCCC2
偶联标记 Un-conjugated
Protein Full name Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
別名 MCCC2; Methylcrotonyl-CoA Carboxylase Subuni 2; MCCB; 3-Methylcrotonyl-CoA Carboxylase Non-Biotin-Containing Subunit; Methylcrotonoyl-CoA Carboxylase Beta Chain, Mitochondrial; 3-Methylcrotonyl-CoA:Carbon Dioxide Ligase Subunit Beta; Methylcrotonoyl-Coenzyme A Carboxylase 2 (Beta); 3-Methylcrotonyl-CoA Carboxylase 2; MCCase Subunit Beta; EC 6.4.1.4; Non-Biotin Containing Subunit Of 3-Methylcrotonyl-CoA Carboxylase; 3-Methylcrotonyl-CoA Carboxylase Non-Biotin Containing Subunit; Methylcrotonoyl-CoA Carboxylase 2 (Beta); Methylcrotonoyl-CoA Carboxylase Beta; Testicular Secretory Protein Li 29; Methylcrotonoyl-CoA Carboxylase 2; Biotin Carboxylase; MCCCbeta; MCCCβ; MCCCB

应用说明

应用建议
应用 推荐稀释比
FACS1-3 µg/1x10^6 cells
IHC-P2-5 µg/ml
WB0.1-0.25 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA.
抗菌剂 0.05% Sodium azide
稳定剂 5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 361884 Rat MCCC2

GeneID: 64087 Human MCCC2

GeneID: 78038 Mouse MCCC2

基因名称 MCCC2
全名 Methylcrotonyl-Coa Carboxylase Subunit 2
背景介绍 This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
生物功能 Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
细胞定位 Mitochondrion
预测分子量 61 kDa
翻译后修饰 Acetylation

检测图片 (6) Click the Picture to Zoom In

  • ARG44227 anti-MCCC2 antibody IHC-P image

    Immunohistochemistry: Human breast cancer stained with ARG44227 anti-MCCC2 antibody at 2 μg/ml dilution.

  • ARG44227 anti-MCCC2 antibody WB image

    Western blot: HepG2 and RT4 stained with ARG44227 anti-MCCC2 antibody at 0.25 μg/mL dilution.

  • ARG44227 anti-MCCC2 antibody IHC-P image

    Immunohistochemistry: Rat kidney stained with ARG44227 anti-MCCC2 antibody at 2 μg/ml dilution.

  • ARG44227 anti-MCCC2 antibody WB image

    Western blot: Rat liver and Rat kidney stained with ARG44227 anti-MCCC2 antibody at 0.25 μg/mL dilution.

  • ARG44227 anti-MCCC2 antibody IHC-P image

    Immunohistochemistry: Mouse kidney stained with ARG44227 anti-MCCC2 antibody at 2 μg/ml dilution.

  • ARG44227 anti-MCCC2 antibody WB image

    Western blot: Mouse liver and Mouse kidney stained with ARG44227 anti-MCCC2 antibody at 0.25 μg/mL dilution.