ARG66646
anti-MART1 / Melan A antibody [SQab19165]
anti-MART1 / Melan A antibody [SQab19165] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab19165] recognizes MART1 / Melan A |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab19165 |
| 同位型 | IgG |
| 靶点名称 | MART1 / Melan A |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminus of Human MART1 / Melan A. |
| 偶联标记 | Un-conjugated |
| 別名 | MART-1; MART1; Protein Melan-A; Antigen SK29-AA; Antigen LB39-AA; Melanoma antigen recognized by T-cells 1 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q16655 Human Melanoma antigen recognized by T-cells 1 |
|---|---|
| 基因名称 | MLANA |
| 全名 | melan-A |
| 生物功能 | Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. [UniProt] |
| 预测分子量 | 13 kDa |
| 翻译后修饰 | Acylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG66646 anti-MART1 / Melan A antibody [SQab19165] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human melanoma tissue stained with ARG66646 anti-MART1 / Melan A antibody [SQab19165]. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).
