ARG46282
anti-MARCHF8 antibody
anti-MARCHF8 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MARCHF8 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MARCHF8 |
| 抗原物种 | Human |
| 抗原 | A 17 amino acid synthetic peptide within the last 50 amino acids of human MARCHF8. |
| 偶联标记 | Un-conjugated |
| 別名 | membrane-associated ring finger (C3HC4) 8; MARCH8; MIR; c-MIR; RNF178; MARCH-VIII; MIR; E3 ubiquitin-protein ligase MARCH8; Cellular modulator of immune recognition |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -332°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5T0T0 Human E3 ubiquitin-protein ligase MARCH8 Swiss-port # Q9DBD2 Mouse E3 ubiquitin-protein ligase MARCH8 |
|---|---|
| 基因名称 | MARCH8 |
| 全名 | membrane-associated ring finger (C3HC4) 8 |
| 背景介绍 | MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010] |
| 生物功能 | E3 ubiquitin-protein ligase that plays several important roles in innate immunity and adaptive immunity. [UniProt] |
| 细胞定位 | Cytoplasm; Endosome; Endoplasmic reticulum membrane; Lysosome membrane; Cytoplasmic vesicle; Cytoplasmic vesicle ; Golgi apparatus. [UniProt] |
| 预测分子量 | 33 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
