ARG58028
anti-MALT1 antibody [MT1/410]
anti-MALT1 antibody [MT1/410] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [MT1/410] recognizes MALT1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MT1/410 |
| 同位型 | IgG1, kappa |
| 靶点名称 | MALT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment corresponding to aa. 701-808 of Human MALT1. |
| 偶联标记 | Un-conjugated |
| 別名 | MALT lymphoma-associated translocation; Paracaspase; MLT1; MLT; EC 3.4.22.-; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; IMD12 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UDY8 Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
|---|---|
| 基因名称 | MALT1 |
| 全名 | MALT1 paracaspase |
| 背景介绍 | This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. [UniProt] |
| 预测分子量 | 92 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58028 anti-MALT1 antibody [MT1/410] IHC-P image
Immunohistochemistry: Paraffin-embedded Human tonsil stained with ARG58028 anti-MALT1 antibody [MT1/410].
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ARG58028 anti-MALT1 antibody [MT1/410] WB image
Western blot: Daudi cell lysate stained with ARG58028 anti-MALT1 antibody [MT1/410].
