ARG45902
anti-MAGI3 antibody
anti-MAGI3 antibody for Western blot,Flow cytometry and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MAGI3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MAGI3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human MAGI3. |
| 偶联标记 | Un-conjugated |
| 別名 | Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 3; MAGI3; KIAA1634; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Membrane-associated guanylate kinase inverted 3; MAGI-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MAGI3 |
| 全名 | Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 3 |
| 背景介绍 | Predicted to enable frizzled binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of JUN kinase activity. Located in cell junction. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2. [UniProt] |
| 细胞定位 | Cell junction; Cell membrane; Membrane; Nucleus; Tight junction. [UniProt] |
| 预测分子量 | 163 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45902 anti-MAGI3 antibody WB image
Western blot: U87-MG stained with ARG45902 anti-MAGI3 antibody at 0.5 μg/ml dilution.
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ARG45902 anti-MAGI3 antibody FACS image
Flow Cytometry: 293T stained with ARG45902 anti-MAGI3 antibody at 1 µg/10^6 cells dilution.
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ARG45902 anti-MAGI3 antibody WB image
Western blot: C6 stained with ARG45902 anti-MAGI3 antibody at 0.5 μg/ml dilution.
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ARG45902 anti-MAGI3 antibody WB image
Western blot: Neuro-2a stained with ARG45902 anti-MAGI3 antibody at 0.5 μg/ml dilution.
