ARG44134
anti-MAEA antibody
anti-MAEA antibody for Flow cytometry,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal recognizes MAEA |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MAEA |
| 抗原物种 | Human |
| 抗原 | Human MAEA recombinant protein (Position: M1-E349). |
| 偶联标记 | Un-conjugated |
| 別名 | MAEA; Macrophage Erythroblast Attacher, E3 Ubiquitin Ligase; P44EMLP; HLC-10; EMP; GID9; Cell Proliferation-Inducing Gene 5 Protein; E3 Ubiquitin-Protein Transferase MAEA; Human Lung Cancer Oncogene 10 Protein; Erythroblast Macrophage Protein; GID Complex Subunit 9, FYV10 Homolog (S. Cerevisiae); GID Complex Subunit 9, FYV10 Homolog; Macrophage Erythroblast Attacher; Lung Cancer-Related Protein 10; EC 2.3.2.27; EMLP; PIG5 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MAEA |
| 全名 | Macrophage Erythroblast Attacher, E3 Ubiquitin Ligase |
| 背景介绍 | This gene encodes a protein that mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. The encoded protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Alternative splicing results in multiple transcript variants. |
| 生物功能 | Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. |
| 细胞定位 | Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Nucleus |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Phosphoprotein, Ubl conjugation |
检测图片 (3) Click the Picture to Zoom In
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ARG44134 anti-MAEA antibody FACS image
Flow Cytometry: U251 stained with ARG44134 anti-MAEA antibody at 1 µg/10^6 cells dilution.
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ARG44134 anti-MAEA antibody WB image
Western blot: Rat brain and PC-12 stained with ARG44134 anti-MAEA antibody at 0.5 μg/ml dilution.
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ARG44134 anti-MAEA antibody WB image
Western blot: Mouse brain stained with ARG44134 anti-MAEA antibody at 0.5 μg/ml dilution.
