ARG54471
anti-Lipoteichoic Acid antibody [96-110]
anti-Lipoteichoic Acid antibody [96-110] for ELISA and Other
Microbiology and Infectious Disease antibody
概述
产品描述 | Mouse Monoclonal antibody [96-110] recognizes Lipoteichoic Acid |
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反应物种 | Other |
应用 | ELISA |
特异性 | This antibody reacts with lipoteichoic acid of Staph epidermidis, Hay strain, as well as clinical strains of Staph. epidermidis (types I, II, and III), Staph. aureus strains 5 and 8, Strep. pyogenes, Strep. fecaelis, and Strep. mutans. It does not react with peptidoglycan of Staph. aureus or peptidoglycanrhamnose, nor does it react with pneumococcal polysaccharides. This antibody does not cross-react with E. coli or H. influenzae type B. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 96-110 |
同位型 | IgG1 |
靶点名称 | Lipoteichoic Acid |
抗原 | Staphylococcus epidermidis, Hay strain (ATCC #55133). |
偶联标记 | Un-conjugated |
应用说明
应用说明 | ELISA: use at 0.1 - 1.0 ug/ml (optimized for LTA on solid phase). Opsonization assay: use at 80 - 160 ug/ml (optimized for Staph. epidermidis, Hay strain). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
形式 | Liquid |
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纯化 | Protein G-purified |
缓冲液 | PBS (pH 7.4) |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
背景介绍 | Lipoteichoic acid (LTA) is the major proinflammatory structure present within the cell wall layer of most gram-positive bacteria. It plays an important role in the initiation and progression of bacterial infection, inflammation, and septic shock. LTA induces several cytokines in vivo, and LTA and peptidoglycan (PepG) synergize to cause the induction of nitric oxide formation which can lead to multiple organ failure. Since LTA is also found in the cell walls of non-pathogenic gram-positive bacteria, it has been suggested that the structure of LTA , and its ability to synergize with PepG, determines the ability of a particular |
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研究领域 | Microbiology and Infectious Disease antibody |