ARG62535
anti-Lewis B antibody [LWB01(2-25LE)]
anti-Lewis B antibody [LWB01(2-25LE)] for IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [LWB01 (2-25LE)] recognizes Lewis B |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | LWB01 (2-25LE) |
| 同位型 | IgG1 |
| 靶点名称 | Lewis B |
| 抗原物种 | Human |
| 抗原 | Human colorectal carcinoma cell line LS174T |
| 偶联标记 | Un-conjugated |
| 別名 | leB; Major airway glycoprotein; Lewis B blood group antigen; Tracheobronchial mucin; mucin; Mucin-5AC; LeB; MUC5; TBM; Gastric mucin; MUC-5AC; Mucin-5 subtype AC, tracheobronchial |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Colon |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified Antibody |
| 缓冲液 | 1X PBS and 0.1% Sodium azide |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MUC5AC |
| 全名 | mucin 5AC, oligomeric mucus/gel-forming |
| 生物功能 | Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. [UniProt] |
| 研究领域 | Cancer antibody; Signaling Transduction antibody |
| 预测分子量 | 586 kDa |
| 翻译后修饰 | C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis. Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide. |
克隆号文献
Glycosylation of mucins present in gastric juice: the effect of helicobacter pylori eradication treatment.
ELISA / Human
Genetic susceptibility to symptomatic norovirus infection in Nicaragua.
WB / Human
The effect of Helicobacter pylori eradication treatment on the MUC 1 and Lewis antigens level in human gastric juice: a preliminary study.
WB / Human
Conjunctival M cells selectively bind and translocate Maackia amurensis leukoagglutinin.
IHC / Guinea pig
Modification of Helicobacter pylori outer membrane protein expression during experimental infection of rhesus macaques.
IHC / Human
