ARG22450
anti-Leukotriene B4 Receptor antibody [202/7B1] (FITC)
anti-Leukotriene B4 Receptor antibody [202/7B1] (FITC) for Flow cytometry,IHC-Frozen sections and Human
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [202/7B1] recognizes Leukotriene B4 Receptor This antibody recognizes Human leukotriene B4 receptor, also known as BLTR, Chemoattractant receptor-like 1, G-protein coupled receptor 16 or P2Y purinoceptor 7. BLTR is a 353 aa, ~40 kDa multipass transmembrane glycoproteinBLTR is expressed by peripheral blood granulocytes and is important in the pro-inflammatory response. |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-Fr |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 202/7B1 |
| 同位型 | IgG2a |
| 靶点名称 | Leukotriene B4 Receptor |
| 抗原物种 | Human |
| 抗原 | HeLa cell transfectants expressing human BLTR. |
| 偶联标记 | FITC |
| 別名 | GPR16; LTB4R1; P2Y purinoceptor 7; BLTR; Chemoattractant receptor-like 1; BLT1; P2Y7; LTB4-R1; LTB4-R 1; G-protein coupled receptor 16; LTBR1; Leukotriene B4 receptor 1; CMKRL1; P2RY7 |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10ul of the suggested working dilution to label 10^6 cells or 100ul whole blood. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide and 1.0% BSA. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1.0% BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LTB4R |
| 全名 | leukotriene B4 receptor |
| 生物功能 | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. [UniProt] |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. |
检测图片 (1) Click the Picture to Zoom In
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ARG22450 anti-Leukotriene B4 Receptor antibody [202/7B1] (FITC) FACS image
Flow Cytometry: Human peripheral blood granulocytes stained with ARG22450 anti-Leukotriene B4 Receptor antibody [202/7B1] (FITC).
