ARG22483
anti-Laminin alpha 5 antibody [4C7 (2D8/33)]
anti-Laminin alpha 5 antibody [4C7 (2D8/33)] for ELISA,ICC/IF,Immunoprecipitation and Human
概述
| 产品描述 | Mouse Monoclonal antibody [4C7 (2D8/33)] recognizes Laminin alpha 5 This antibody recognizes the laminin alpha 5 chain also known as Laminin-10 subunit alpha, Laminin-11 subunit alpha or Laminin-15 subunit alpha. Laminin is a complex glycoprotein composed of three polypeptide chain complexes. Laminin alpha 5 is expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta, there is little or no expression in brain and liver. |
|---|---|
| 反应物种 | Hu |
| 不反应物种 | Ms, Rat |
| 应用 | ELISA, ICC/IF, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 4C7 (2D8/33) |
| 同位型 | IgG2a |
| 靶点名称 | Laminin alpha 5 |
| 抗原物种 | Human |
| 抗原 | Purified human laminin. |
| 偶联标记 | Un-conjugated |
| 別名 | Laminin-11 subunit alpha; Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-15 subunit alpha |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | Ascites and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LAMA5 |
| 全名 | laminin, alpha 5 |
| 背景介绍 | This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013] |
| 生物功能 | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. [UniProt] |
| 预测分子量 | 400 kDa |
