ARG55913
anti-Lamin B2 antibody
anti-Lamin B2 antibody for Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Lamin B2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | Lamin B2 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human Lamin B2 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | Lamin-B2; LMN2; LAMB2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS (pH 7.4), 0.03% Proclin-300 and 50% Glycerol |
| 抗菌剂 | 0.03% Proclin-300 |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LMNB2 |
| 全名 | lamin B2 |
| 背景介绍 | This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012] |
| 生物功能 | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. [UniProt] |
| 细胞定位 | Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side. |
| 预测分子量 | 70 kDa |
| 翻译后修饰 | B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. |
检测图片 (2) Click the Picture to Zoom In
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ARG55913 anti-Lamin B2 antibody WB image
Western blot: Jurkat cell lysate stained with ARG55913 anti-Lamin B2 antibody at 1:500 dilution.
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ARG55913 anti-Lamin B2 antibody IP image
Immunoprecipitation: HeLa cell lysates were immunoprecipitated and stained with ARG55913 anti-Lamin B2 antibody.
