ARG64744

anti-Lactoferrin antibody

anti-Lactoferrin antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody

概述

产品描述 Goat Polyclonal antibody recognizes Lactoferrin
反应物种 Hu
应用 IHC-P, WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 Lactoferrin
抗原物种 Human
抗原 C-ENYKSQQSSDPDP
偶联标记 Un-conjugated
別名 LF; Lfcin-H; HEL110; Lactoferrin; Lactotransferrin; Growth-inhibiting protein 12; GIG12; Talalactoferrin; EC 3.4.21.-; HLF2

应用说明

应用建议
应用 推荐稀释比
IHC-P2 - 4 µg/ml
WB0.05 - 0.2 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Peripheral blood mononucleocyte
实际分子量 ~ 85 kDa

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 4057 Human LTF

Swiss-port # P02788 Human Lactotransferrin

背景介绍 This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
研究领域 Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量 78 kDa
翻译后修饰 Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391.
Poly-N-acetyllactosaminic carbohydrate moiety seems to be needed for TLR4 activation.

检测图片 (2) Click the Picture to Zoom In

  • ARG64744 anti-Lactoferrin antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human blood vessel tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64744 anti-Lactoferrin antibody at 2 µg/ml dilution followed by AP-staining.

  • ARG64744 anti-Lactoferrin antibody WB image

    Western blot: 35 µg of peripheral blood mononucleocyte lysate (in RIPA buffer) stained with ARG64744 anti-Lactoferrin antibody at 0.05 µg/ml dilution and incubated at RT for 1 hour.